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Comparison of Mechanical Insufflation-exsufflation and Percussors in the Treatment of Lung Infections for Children with Cerebral Palsy

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Background: Children with cerebral palsy (CP) in particular require assistance with airway clearance due to weaker muscle strength. Successful airway clearance requires both mucociliary and cough clearance. Mucociliary clearance can be assisted with percussion and postural drainage, and cough clearance can be assisted by mechanical insufflation-exsufflation (MI-E). No previous study of MI-E focuses on CP children.Methods: In this prospective study, we compared the airway clearance efficiency of MI-E versus percussor for cerebral palsy children with lower respiratory tract infections. The randomized treatments persisted for one week, and their efficiency in airway clearance were compared. The safety and tolerance of MI-E/percussor in these patients were also evaluated.Results: A total of 32 cerebral palsy children with lower respiratory tract infections were enrolled in this study, including 16 of who received MI-E and 16 received percussor. There were no differences between these two groups in terms of basic demographic data including age, gender, initial fever duration and initial laboratory data. The MI-E group had a lesser sputum amount than the percussor group from the fourth day after treatment (sputum amount score 2.1±0.5 vs. 2.8±0.8; p=0.014). Both methods were well tolerated by the patients without any adverse side effects.Conclusions: The MI-E is superior to percussor for CP children with lower airway infections in sputum clearance.

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