腎臟移植術後之新發糖尿病

移植術後的新發糖尿病(new-onset diabetes after transplantation, NODAT) 是腎臟移植術後主要且常見的併發症，而因NODAT 所產生的併發症，嚴重者將導致移植腎臟功能衰竭及患者死亡，且增加心血管疾病的發病率。故本篇文章旨在探究腎臟移植NODAT 之無法修正與可修正的危險因子，並提供移植術前評估、移植術後血糖監測與免疫抑制劑臨床處置原則。若能早期偵測危險因子，適時提供預防措施與臨床處置，減少併發症發生，將有助於提升腎臟移植術後的長期存活率。

Keywords

腎臟移植；移植術後新發糖尿病；糖化血色素

Parallel abstracts

A diagnosis of new-onset diabetes after transplantation (NODAT) is a common complication after kidney transplantation. Most importantly, NODAT affects graft and patient survival, and increases the incidence of post-transplant cardiovascular disease. In this review paper, non-modifiable and modifiable risk factors for NODAT are discussed. In addition, pre-transplant evaluation and post-transplant monitoring of glucose and management of immunosuppression are discussed. If early detection of risk factor for new-onset diabetes, the timely prevention and clinical management, reduce complications, it will help to improve the long-term survival after kidney transplantation.

Parallel keywords

kidney transplantation ； new-onset diabetes after transplantation ； HbA1C

Read-around

周桂君、李明哲、蔡娟秀（2016）。糖尿病患者之腎臟移植。腎臟與透析，28(2)，72-75。https://doi.org/10.6340/KD.2016.28(2).05
洪啟峰、楊晨洸、徐國雄、賀昊中（2016）。腎臟移植術後之手術併發症。腎臟與透析，28(1)，27-30。https://doi.org/10.6340/KD.2016.28(1).07
Lai, C. P., Chang, C. C., Yang, Y., Wen, Y. K., Chiou, P. F., Chen, M. L., Yeh, K. T., & Lin, Y. M. (2010). 糖尿病人的非糖尿型腎病變：台灣單一醫學中心之臨床病理研究. Acta Nephrologica, 24(3), 157-166. https://www.airitilibrary.com/Article/Detail?DocID=10131671-201007-201012230024-201012230024-157-166
顧進裕（1991）。糖尿病腎病變之處理。當代醫學，(217)，901-904。https://doi.org/10.29941/MT.199111.0006
Crews, D. C., Bello, A. K., Saadi, G., & Committee, W. K. D. S. (2018). Burden, Access, and Disparities in Kidney Disease. Acta Nephrologica, 32(3), 98-107. https://doi.org/10.6221/AN.201809_32(3).0002

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腎臟移植術後之新發糖尿病

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