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末期腎臟病病人合併糖尿病之照護

The Care of End-Stage Renal Disease Patients With Diabetes Mellitus

摘要


慢性腎臟病是糖尿病常見的併發症,也是造成末期腎臟病(end-stage renal disease, ESRD)最常見的原因,糖尿病的盛行率在全世界都持續增加中,未來慢性腎臟病的患者也會逐年增加,適當的血糖控制避免患者進入到ESRD及其他併發症,以及ESRD的糖尿病照護都相當重要,然而治療末期腎臟病患者之糖尿病是相當具有挑戰性的,因為血液中葡萄糖恆定的改變、不確定的血糖控制指標及降血糖藥物在腎功能不全患者之藥物動力學改變等,本篇會更進一步介紹。

並列摘要


Chronic kidney disease (CKD) is a common complication of diabetes mellitus and the most common cause of end-stage renal disease (ESRD). In recent years, the prevalence of diabetes had continued to increase throughout the world. The number of patients with CKD will also increase. Appropriate glycemic control in patients with diabetes to prevent ESRD and other complications, as well as diabetes care in ESRD patients are very important. The treatment of diabetes in ESRD patients is challenging. The changes in glucose homeostasis, the unclear accuracy of glycemic control metrics, and changes in pharmacokinetics of glucose lowering agents in patients with renal insufficiency are the main causes. I will be further described in this article.

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