Sleeping disturbance is a common syndrome of hemodialysis. When the quality of sleep is poor, it will lead to the risk of cardiovascular risk, weakened immunity and dementia in the elderly, resulting in a higher mortality rate. Although insomnia is an important problem in hemodialysis patients, there are few related studies and reports. This article reviews non-pharmacological and new pharmacological treatments for insomnia and provides methods and suggestions for the management of insomnia in hemodialysis patients.