- 期刊
Duodenal Adenocarcinoma with Liver Metastasis and Elevated Serum Alpha-fetoprotein
十二指腸腺癌合併肝臟轉移及血清α胎兒蛋白升高
摘要
我們報告一個十二指腸腺癌合併肝臟轉移伴隨α胎兒蛋白血清值昇高的病例。這位72歲的女性病人因為連續四天解黑便而住院。上消化道內視鏡檢查發現十二指腸有一個表面有潰瘍的腫瘤外。亦在肝臟發現多個腫瘤性病灶。病人的α胎兒蛋白血清值高達3973ng/Ml（正常值小於20ng/Ml）。此病人接受超音波導引下的肝臟切片檢查，結果肝臟腫瘤的病理切片報告為轉移性的腺癌。我們發現此一升高的血清α胎兒蛋白應該是由製造α胎兒蛋白的十二指腸腺癌所產生。
並列摘要
We report a 72-year-old woman with metastatic liver tumor presenting with elevated alphafetoprotein (AFP) due to duodenal adenocarcinoma. This patient was admitted because of melena for 4 days. Upper gastrointestinal endoscopic examination showed an ulcerative tumor in the first and second portion of the duodenum. Endoscopic biopsy of the duodenal tumor revealed a moderately differentiated adenocarcinoma. Computed tomography of the abdomen demonstrated a tumor in the duodenum and multiple tumor lesions in the liver. The laboratory data showed that the serum AFP level was 3973 ng/mL (reference range, ＜ 20 ng/mL). A sonographic-guided liver biopsy was performed which revealed a metastatic adenocarcinoma. We found that the highly elevated serum AFP might have originated from the duodenal cancer with liver metastasis.