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從肺論治反覆性著床失敗病例報告

Treatment in Recurrent implantation failure based on traditional Chinese medicine viscera view of lung: A case report

摘要


反覆性著床失敗(Recurrent implantation failure; RIF)是指40歲以下女性在至少3個新鮮或冷凍週期中移植至少4個優質胚胎後未能達到臨床懷孕(人類絨毛膜性腺激素β-HCG>25mlU/mL,或者尿妊娠試驗陽性)。成功懷孕的因素包括健康的胚胎,良好的子宮環境與適合胚胎發育的子宮內膜,正常的荷爾蒙分泌或補充,無自體免疫系統排斥的問題,研究顯示35歲女性,重複、反覆植入染色體整倍體(euploidy)胚胎三次失敗的機率小於5%。本篇病例報告介紹一個反覆植入優質胚胎失敗7次的案例,利用月經周期療法搭配中醫臟腑調節,配合西醫自然週期植入療程,達到成功受孕的目的。

並列摘要


Recurrent implantation failure refers to failure to achieve a clinical pregnancy after transfer of at least four good-quality embryos in a minimum of three fresh or frozen cycles in a woman under the age of 40 years. Factors for a successful pregnancy include a healthy embryo, a good uterine environment and an endometrium suitable for embryonic development, normal hormone secretion or supplementation, and no autoimmune rejection problems. Studies have shown that RIF probability is less than 5%. This article introduces a case who had failed 7 times high-quality embryos implantation in the past three years. Use menstrual cycle therapy combined with TCM viscera regulation to achieve successful pregnancy.

參考文獻


ESHRE Special Interest Group of Embryology and Alpha Scientists in Reproductive Medicine(2017).The Vienna consensus: report of an expert meeting on the development of ART laboratory performance indicators.Reprod Biomed Online.35(5),494-510.
Coughlan, C,Ledger, W,Wang, Q(2014).Recurrent implantation failure: definition and management.Reprod Biomed Online Jan.28(1),14-38.
Pirtea, Paul,De Ziegler, Dominique,Tao, Xin(2021).Rate of true recurrent implantation failure is low: results of three successive frozen euploid single embryo transfers.Fertil Steril.115(1),45-53.
Blanco-Breindel MF, Singh M, Kahn J. Endometrial Receptivity. [Updated 2023 Jun 7]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK587449/
繆江霞(2019).中醫改善子宮內膜容受性以提高受孕率的思路和方法.香港中醫雜誌.14(2),41-43.

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