反覆性著床失敗(Recurrent implantation failure; RIF)是指40歲以下女性在至少3個新鮮或冷凍週期中移植至少4個優質胚胎後未能達到臨床懷孕(人類絨毛膜性腺激素β-HCG>25mlU/mL,或者尿妊娠試驗陽性)。成功懷孕的因素包括健康的胚胎,良好的子宮環境與適合胚胎發育的子宮內膜,正常的荷爾蒙分泌或補充,無自體免疫系統排斥的問題,研究顯示35歲女性,重複、反覆植入染色體整倍體(euploidy)胚胎三次失敗的機率小於5%。本篇病例報告介紹一個反覆植入優質胚胎失敗7次的案例,利用月經周期療法搭配中醫臟腑調節,配合西醫自然週期植入療程,達到成功受孕的目的。
Recurrent implantation failure refers to failure to achieve a clinical pregnancy after transfer of at least four good-quality embryos in a minimum of three fresh or frozen cycles in a woman under the age of 40 years. Factors for a successful pregnancy include a healthy embryo, a good uterine environment and an endometrium suitable for embryonic development, normal hormone secretion or supplementation, and no autoimmune rejection problems. Studies have shown that RIF probability is less than 5%. This article introduces a case who had failed 7 times high-quality embryos implantation in the past three years. Use menstrual cycle therapy combined with TCM viscera regulation to achieve successful pregnancy.