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中藥成功治療卵巢早衰案例

Successful Premature Ovarian Failure Treatment with Traditional Chinese Medicine: A Case Report

摘要


此病案為一名39歲女性,於37歲時自然產下一胎,自第一胎產後開始月經不規則。備孕一年多仍未成功懷孕,至林口長庚醫院婦產科內分泌生殖門診就診,西醫抽血檢驗後診斷卵巢早衰,由西醫轉介中醫婦科門診合併中西醫治療。經中醫治療後,月經來潮三個月、抽血FSH回復至19.5mIU/ml、超音波檢查竇卵泡計數(AFC)為3,並成功於2020/05/08西醫試管嬰兒療程順利取卵,並成功發育成胚胎進行冷凍。顯示中藥於卵巢功能之恢復有一定程度上的幫助。

並列摘要


According to the definition of Premature Ovarian Failure (POF) by the European Society of Human Reproduction and Embryology (ESHRE), it refers to amenorrhea or irregular menstruation for more than four consecutive cycles in women of childbearing age before the age of 40, with FSH >25 mIU/ml on two occasions >4 weeks apart. In addition, patients with POF are often observed to have decreased anti-mullerian hormone (AMH) level and decreased antral follicle count (AFC). The etiology of primary premature ovarian failure is currently unknown, and western medical treatment mainly focused on hormonal therapy. This case report is a 39-year-old woman, G1P1, who began to have irregular menstruation after giving birth to her first child. With subsequent failed attempts to conceive for more than a year, she visited our infertility clinic where she was diagnosed with POF. She received clomid treatment but the result was unsatisfied. Thus, she was referred to the Chinese Medicine Gynecology Clinic and received integrated treatment with both Western and Chinese medicines.

參考文獻


衛生福利部國民健康署 • 衛生福利部國民健康署 110 年台灣地區人工生殖施行結果報告2023 [Available from: https://www.hpa.gov.tw/File/Attach/17531/File_22374.pdf.
Carson, SA,Kallen, AN(2021).Diagnosis and Management of Infertility: A Review.JAMA..326(1),65-76.
Ishizuka, B(2021).Current Understanding of the Etiology, Symptomatology, and Treatment Options in Premature Ovarian Insufficiency (POI).Front Endocrinol.12,626924.
(2021).Fertility evaluation of infertile women: a committee opinion.Fertil Steril.116(5),1255-1265.
Rafique, S,Sterling, EW,Nelson, LM(2012).A new approach to primary ovarian insufficiency.Obstet Gynecol Clin North Am.39(4),567-586.

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