一般而言,白血病的特異性併發症,時常早期出現於口腔,因此有關口腔內的各種突發性臨床徵候和白血病的早期診斷有非常密切的關係。本研究取材自本院69年至72年住院之白血病患者230位,統計及分析患者初診時, 其病灶特性、年齡及常規血液檢查、及口內臨床併發症的種類與發生率。結果簡單摘要如下:1.白血病之種類,在年齡分佈上,可能具有特 異性。(慢性骨髓性白血病除外) 2.男性罹患率較女性高。3.患者主訴症狀中,最常見之口內併發症是頸部淋巴腺腫大、咽喉疼痛、口內出血、口腔潰瘍、牙齦腫大。 4.急性淋巴性白血病罹患年齡一般大部份小於 10歲;急性骨髓性白血病罹患年齡大部份 小於30歲。 5.患者主訴的早期特異性之口內病徵對於白血病的早期診斷具有臨床價值性。
A retrospective study of 230 patients with leukemia was conducted to detterming nature and prevalence ofclinical considerations in dental field occuring at the initial diagnostic period. The results were summarized as follows: 1. The age distribution of patients is related to the type of leukemia,except CML. 2. A slight higher predominance of leukemia in males than females. 3. The most common oral manifestations of leukemia are: lymphaenopathy, laryngeal pain, oral bleeding, oral ulcer, and gingival enlargement. 4. ALL and AML are seen primarily in patients less than 10 years (63;7% and 30 years (72%) of age respectively. s. The feature and frequency of oral manifestations in leukemic patients emphasize the importance of careful oral examination and history taking in leading to the diagnosis and may be of value in detennining the treatment of the disease.