- 期刊
Chronic Osteomyelitis of the Mandible as a Complication of Osteopetrosis - A Case Report
骨質石化症之併發症
摘要
骨質石化症(Osteopetrosis)叉名大理石骨症(marble bone disease)。為一罕見而原因不明疾病;在1907年首先由德國放射科醫師 Heinrich - Albergs -Schönberg提出報告,迄今僅有三、四百個病例被報告過。其特徵為廣泛性的骨密度增加,緻密骨或皮質骨( cortical bone)與海綿骨(cancellous bone)被一種無結構而密度高的骨所取代。此種結構的骨脆而易斷,而且由於骨中血管大部分被增生的高密度骨所取代,所以在血液供給不足的情況下, 骨質石化症常伴隨有骨髓炎及病理性骨折的發生 。 本篇所討論的病例是一位患有骨質石化症 的60歲男性病人,在1985年時經拔牙後發生下顎骨骨髓炎,而在治療過程中,更發生病理性 骨折,然後經恥骨移植並加以固定,癒後情況 順利。
關鍵字
無資料並列摘要
Osteopetrosis, also called Marble bone disease, is an uncommon pathologic condition of bone with uncertain etiology. The first case of this generalized. sclerotic disorder of the skeleton system was reported by a German radiologist, Heinrich Albers-Schönberg in 1907. Since that time, little more than 300 cases have been reported in the world literatures. The disease is characterized by a symmetrical, diffused and generalized increase in bone density. The nonnal cortical and cancellous bone are replaced by excessively dense structureless bone arranged in random architecture. Pathologic fractures and osteomyelitis accompany osteopetrosis due to the tickening of the bone cortices and the generalized obliterated medullary spaces of the bone. We reported a 60-year-old male patient who suffered from oste.opetrosis. Following extraction of the teeth, osteomyelitis and bone grafting, the patient receIved follow-up examination at Kaohsiung Medical College. TIle clinical presentation of the oral lesions, the diagnosis and treatment are discussed.