肺癌轉移至牙周－病例報告

Metastatic Lung Carcinoma Involving the Periodontium - Case Report

童維康(Wei-Kang Tung) ； 林坤霖(Kun-Lin Lin) ； 葉啟偉(Chi-Wei Yeh) ； 張廷安(Ting-An Chang) ； 黃麗珠(Li-Ju Huang)

《中華民國耳鼻喉科醫學雜誌》 35卷1期 (2000/01) Pp. 83-86

https://doi.org/10.6286/2000.35.1.83

摘要

在惡性腫瘤的自然史中，口腔的轉移並不常見，其中最常轉移到下颌骨骨髓，而轉移到口腔中的軟組織或牙周則極其少見。本院經歷1例肺癌的75歲男性，在做完放射治療1個月後因為下顎門齒搖動去拔牙，傷口並未癒合，反而長出一快速長大的腫瘤，此牙齦腫瘤經組織學化驗為一具有巨大細胞的大型細胞癌，與其本身肺癌之細胞學特徵相同，此後病人僅接受支持性療法，最後死於多器官衰竭。此例提醒了當病患具呼吸或腸胃道腫瘤時應注意是否有口腔轉移之可能性。

關鍵字

肺癌 ； 轉移 ； 牙周

並列摘要

In the natural history of malignant tumours, oral metastasis is uncommon. Mandibular bone marrow is the most common site affected. Metastasis to the oral soft tissues or peri-odontium is extremely rare. A case of metastatic lung carcinoma to the lower gingiva in a 75-year-old man is presented. The rapidly-growing gingival tumor appeared at an unhealed tooth-extraction site one month after the completion of radiotherapy for lung carcinoma. The gingival tumor was histopathologically diagnosed as large cell carcinoma with giant cells which was identical to the cytological feature of the previous lung carci-noma. The patient received supportive treatment but eventually died due to multi-organ failure. Therefore, more attention should be paid to the differential diagnosis of oral lesions if aerodigestive tract malignancy is present.

並列關鍵字

lung carcinoma ； metastasis ； periodontium