- 期刊
眩暈合併高膽固醇血症患者的頸動脈超音波檢查結果
Carotid Dopscan Findings in Vertiginous Patients with Hypercholesterolemia
摘要
背景：針對眩暈合併高膽固醇血症患者的頸動脈內中膜厚度及椎體基底動脈的血流速度變化情形，目前尚無文獻報告。由於動脈內中膜厚度可做為早期動脈粥狀硬化的指標，所以本研究針對眩暈合併高膽固醇血症患者，施行非侵襲性的頸部超音波檢查，並且報告我們的經驗與檢查結果。 方法：2000年1月至12月之間來本院耳鼻喉科門診就診的眩暈患者，經排除良性陳發性姿態性眩暈、腦部腫瘤、腦溢血、腦栓塞與其他腦部重大疾病後，抽血檢測患者血中膽固醇濃度，針對眩暈合併高膽固醇血症患者，施行非侵襲性的頸部超音波檢查。 結果：共有32名患者願意接受頸部超音波檢查，其中男13名，女19名，平均年齡58歲。檢查結果發現：1）隨著年齡的增加，上頸動脈內中膜厚度過度增厚的數目也會跟著增加。2）隨著年齡的增加，頸動脈的最大內中膜厚度也跟著增加。3）男性的頸動脈最大內中膜厚度，較女性為高。4）隨著血中膽固醇濃度的增高，顱外椎體動脈血流速度過低的機會，也會跟著增加。 結論：針對眩暈合併高膽固醇血症患者，隨著患者年齡的增加，頸動脈內中膜厚度過度增厚情形，也會跟著增加；隨著患者血中膽固醇濃度的增高，其顱外椎體動脈血流速度過低的機會，也會跟著增加。
並列摘要
BACKGROUND: Regarding vertiginous patients with hypercholesterolemia, we found no reports described their carotid Dopscan findings explicitly. The purpose of this study was to present the carotid Dopscan findings for vertiginous patients with hypercholestero-lemia. METHODS: After excluding BPPV, brain tumor, or brain infarction, 32 vertiginous patients with hypercholesterolemia were advised to receive carotid Dopscan examination between January 2000 and December 2000. We not only measured the intima-media thick-ness for the carotid arteries and extracranial vertebral arteries, but also recorded the peak systolic and end diastolic pressures for the intracranial vertebral and basilar arteries. RESULTS: The Carotid Dopscan examination findings are as follows: 1) The number of intima-media over-thickness increased as patient’s age increased. 2) The largest intima-media thickness increased as patient’s age increased. 3) The largest intima-media thick-ness was larger in men than those in women. 4) The possibility of low blood flow velocity in the extracranial vertebral artery increased as the degree of hypercholesterolemia increased. CONCLUSIONS: For vertiginous patients with hypercholesterolemia, not only the patien-t’s age may affect the carotid intima-media thickness, but also the hypercholesterolemia may increase the risk of low blood flow velocity in the extracranial vertebral arteries.