- 期刊
單一劑量Ofloxacin 治療急性下泌尿道感染
Single-Dose Ofloxacin for the Treatment of Uncomplicated Lower Urinary Tract Infections
摘要
Seventy-three patients who experienced acute uncomplicated lower urinary tract infections with mainly gram negative becteria received a single dose 200mg ofloxacin treatment. Urinary leukocyte count returned to normal level in 65.1% of the patients three day after drug administration. Patients with significant bacteriuria achieved the best result (sure rate 75%). Age and severity of pyuria had no significant influence on the result. Adverse drug reaction, with G-I upset the predominant discomfort, occurred for 9.09% of the patients. Compared with traditional long term (7-14days) or short duration (1-3 days) treatment, single dose therapy has the following advantages: (1)lower cost; (2) less chance of inducing resistant strain microorganism; (3) fewer side effect; (4)better patient compliance. It would be worthwhile to undertake extensive study of clinical applications especially in Taiwan where the medical budget is rising and bacterial resistant strains are common.
並列摘要
Seventy-three patients who experienced acute uncomplicated lower urinary tract infections with mainly gram negative becteria received a single dose 200mg ofloxacin treatment. Urinary leukocyte count returned to normal level in 65.1% of the patients three day after drug administration. Patients with significant bacteriuria achieved the best result (sure rate 75%). Age and severity of pyuria had no significant influence on the result. Adverse drug reaction, with G-I upset the predominant discomfort, occurred for 9.09% of the patients. Compared with traditional long term (7-14days) or short duration (1-3 days) treatment, single dose therapy has the following advantages: (1)lower cost; (2) less chance of inducing resistant strain microorganism; (3) fewer side effect; (4)better patient compliance. It would be worthwhile to undertake extensive study of clinical applications especially in Taiwan where the medical budget is rising and bacterial resistant strains are common.