慢性鼻竇炎是小兒常見的疾病之一,了解小兒慢性鼻竇炎的細菌學,對於治療小兒慢性鼻竇炎的抗生素選擇是相當重要的。自1994年7月至1996年8月間,本科計有28名小兒病患因慢性鼻竇炎或鼻內息肉入院接受功能性鼻竇內視鏡手術,其中男性11名、女性17名,年齡則介於5歲至18歲,平均為11歲。我們於手術的同時在鼻竇內直接取樣做細菌培養,結果以coagulase-negative staphylococcus(佔42.9%)、Staphyloclccus aureus(佔32.1%)、α – hemolytic streptococcus(佔28.6%)及Streptococcus pneumoniae(佔25.0%)佔多數,而無任何細菌生長者有4例,佔14.3%。在細菌對抗生素敏感試驗方面,上述4種細菌對penicillin具抗藥性的菌株大於80%(30/36),因此於治療小兒慢性鼻竇炎時,這個結果可以提供臨床醫師於選擇抗生素時的一個依據。
Chronic paranasal sinusitis is a rela-tively common clinical disorder in children. Very few studies have involved the microbe-ology of chronic sinusitis in children. Some studies that address this issue have shown different results. To research of the bacteri-ology of chronic sinusitis in children, we did bacterial cultures from sinuses of 28 children who undergoing surgical inter-vention. The predominant isolated organ-isms were coagulase-negative staphyloco-ccus (42.9%), staphylococcus aureus (32.1%), α –hemolytic streptococcus (28.6%) and streptococcus pneumoniae (25.0%). In 4 cases, the cultures were no growth. More than 80% of the organisms were resistant to penicillin. No anaerobes have been cultured. The role of anaerbes in the bacteriology of chronic sinusitis in children is unclear.