- 期刊
下頜腺腫瘤－本土病低惡性率之臨床意義
Submandibular gland Tumors – Local Clinical Implications of Their Low Malignancy Rates
摘要
背景：下頜腺腫瘤，根據歐義之文獻報告，其惡性比率大多高於40%。然而本科於臨床經驗上，發現下頜腺腫瘤之惡性比率並不如文獻報告之高，其臨床意義值得進一步研究。 方法：收集自1986年1月至1997年6月，於本院手術經病理檢查證實為下頜腺腫瘤之病例共126例，加以統計分析。 結果：良性腫瘤共106例（佔84.1%），惡性腫瘤僅20例（佔15.9%）；平均年齡，良性腫瘤36.9歲，惡性腫瘤51.2歲；男女比例，良性腫瘤男：女=1：1.52，惡性腫瘤男：女=1：0.53；腫瘤形態，良性腫瘤以混合瘤103例（97.1％）最多，惡性腫瘤20例中，腺樣囊狀癌10例）（50%），惡混合瘤6例（30%），黏液上皮癌2例（10%），腺癌和惡性淋巴上皮病變各1例。預後方面，良性腫瘤經手術後，追蹤至今，並無復發之病例，惡性腫瘤經懺術及放射治療後，其2年存活率為72.2%（13/18），惡性腫瘤的5年存活率則伱為52.9%（9/17）。 結論：統計126例下頜腺腫瘤之病例，其惡性比率僅15.9%，遠低於國外35%-50%之惡性比率，此是否與人種、飲食習慣等因素有關，值得進一步研究。
並列摘要
Background: Accrding to previous reports, the malignancy rate of submandibular gland tumors is about 35%-50%. However, the rate has seemed much lower in Taiwan. Further studies of the epidemiology and the possible etiology of this disease are needed. Method: We did a retrospective study of 126 patients with submandibular gland tumors who had undergone operations at our hospital from January 1986 to June 1997. Of these, 71 were womenand 55 men, with ages ranging from 12 years old to 74 years old. The histological findings, age, sex ratio and prognosis were all analysed. Results: Of the 126 submandibular gland tumors, 106 were benign and 20 were malignant. The malignancy rate was only 15.9%. The average age of persone with benign tumors was 36.9 years and the average age of those with malignancy was 51.2 years. The male to female eatio was 1:1.52for benign tumoes and 1:0.53 for malignant tumors. Of the 106 benign tumors, 103 were plmorphic adenomas. Of the 20 malignant tumors, 10 were adenoid cystic carcinomas. 6were malignant mixed tumors and 2 were mucoepidermoid carcinomas. No recurrence was found in any benign tumors postoperatively. The 2-year survival rate for persons with malignant tumors were 72.2% and the 5-year survival rate was 52.9%. Conclusion: The malignancy rate of the 126 submandibular gland tumors was only 15.9%, much lower than the eates in previous reports. Further study is suggested about the corelations between the malignancy rates and humen eaces, dietary, etc.