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摘要


喉部的神經內分泌腫瘤 (neuroendocrine neoplasms)是一群極為少見的疾病,本院於1994年10月經驗1例。患者為74歲男性,經喉部顯微手術以雷射切除病灶,病理診斷為右側杓狀軟骨的非典型類型癌 (atypical carcinoid tumor),屬神經內分泌腫瘤中上皮起源的第一大類。術後在門診追蹤1年10月,未有復發現象。因屬罕見,特提出報告,並對其臨床表徵,診斷治療及病理學加以討論。

關鍵字

分泌腫瘤 非典型類癌

並列摘要


Neuroendocrine neoplasms of the larynx are a rare group of tumors that are thought to be arised from amine precursor uptake and decarboxylase (APUD) cells or the dispersed neuroendocrine cell system. Suggested embryonic sites of origin include the neural crest, ectoderm, and endoderm. The recent World Health Organization (WHO) classification scheme divides these tumors into three groups: carcinoid tumor, atypical carcinoid tumor, and small cell carcinoma. In October 1994, we encountered a 74 year old man who had suffered from dysphagia for several months. A larynogoscopic biopsy on a whitish irregular lesion at the right arytenoids was perfomed. The pathologic report was an atypical tumor. Computed tomography of the neck showed no evidence of regional metastasis. The tumor was removed by laser laryngomicrosurgery. He has been regularly followed for 22 months. No evidence of recurrence was noted.

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