The purpose of this study is to examine the relationship between emotional labor and physical-mental health and to analyze the moderating effect of self-monitoring. A total of 324 valid questionnaires were collected from teachers of special education school in southern Taiwan. Partial least squares (PLS) structural equation modeling was applied. One of the results showed that teachers' emotional labor didn't damage teachers' physical-mental health. It also proved that self-monitoring of emotional labor had a part moderating effect on physical-mental health; that is, teachers with higher self-monitoring, the less unhealthy physical-mental problem would happen. Finally, the results of the study could be used as a reference for the administration of education.