馬偕紀念醫院在過去10年間共有6例經開刀病理切片證實的異位性胰臟,其中4例是在近一年內發現的。發生年齡自30歲到64歲,平均47歲。其中男性5名,女性1名。發生部位在胃、十二指腸、空腸各有2例。有症狀的4例皆曾主訴上腹疼痛,3例有上消化道出血病史,術前診斷爲穿孔性消化潰瘍者1例,胃賓部潰瘍1例,胃息肉疑惡性腫瘤者1例和十二指腸腫瘤1例。無症狀的2例是在不相關的開腹手術中偶然發現的,位置均在空腸,腫塊較大。6例中只有1例。具有異位元性胰臟典型的特徵,有3例曾經內視鏡檢查生檢,但全部無法得到正確的術前診斷。對於異位性胰臟的臨床表徵、上消化道X光系列檢查和內視鏡檢查的特徵提高警覺,相信可以改善術前診斷的正確率。
During a period of 10 years, there were 6 pathologically verified heterotopic pancreas cases in Taipei Mackay Memorial Hospital, 4 of which were seen within the last one year. There were five male and one female. The age ranged from 30 to 64 years with an average of 47 years. Distribution of the heterotopic pancreatic tissue was two each in the stomach, duodenum and jejunum. Four of the six cases (66.7%) had significant clinical symptoms related to the presence ef heterotopic pancreas, who all complained of epigastric pain. Three had history of upper G-I tract bleeding, acute or chronic. The preoperative diagnoses were PPU (1 case), gastric ulcer on the antrum (1 case), gastric polyp suspected of malignancy (1 case), and duodenal submucosal tumor (1 case). The remaining two asymptomatic cases, who were discovered incidentally during laparotmy for cervical cancer and abdominal stab injury respectively, had lager masses that located in the jejunum. None of our cases was correctly diagnosed before operation, though one case had typical characters of heterotopic pancreas, and three underwent endoscopic biopsy. High index of suspicion of heterotopic pancreas and familiarity with its radiographic and endoscopic features may improve the accuracy in preoperative diagnosis.