- 期刊
Elimination of Multiple Hyperplastic Polyps by Eradication of Helicobacter Pylori: Report of a Case
幽門螺旋桿菌根除後胃增殖性息肉的消除：一病例報告
摘要
增殖性息肉是最常見的胃上皮性息肉，少有惡性化現象；可能是由於慢性發炎造成胃黏膜的增殖性反應所形成。大的胃增殖性息肉有較高的惡性可能，並傾向造成疼痛、出血、胃出口阻塞等，故一般建議將較大的胃增殖性息肉切除。近年來發現幽門螺旋桿菌和胃增殖性息肉有密切的關係；根除幽門螺旋桿菌後可以使胃增殖性息肉消失。一位55歲男性，於23年前因潰瘍出血接受過部分胃切除。近半年來上腹部不適、食慾不振，於本院接受上消化道內視鏡及切片檢查，發現胃殘存部分有多個增殖性息肉，最大者直徑達1.8公分，並合併幽門螺旋桿菌感染。經三合一療法根除幽門螺旋桿菌後，病人的臨床症狀改善，且胃增殖性息肉有減少現象。於九個月後的內視鏡追蹤，顯示息肉已完全消失。由本個案經驗來看，胃增殖性息肉的患者，應檢測有無幽門螺旋桿菌感染。如有幽門螺旋桿菌感染，根除幽門螺旋桿菌可能使胃增殖性息肉完全消失。
並列摘要
Gastric hyperplastic polyps have been traditionally treated by endoscopic removal, if they are large in size. In recent years there were reports relating Helicobacter pylon (Hp) infection with hyperplastic polyps, and elimination of polyps after Hp clearance. We herein present a case with disappearance of large hyperplastic polyps after eradication of Hp. A 55 year-old male had epigastric discomfort, poor appetite and weight loss for months. UGI endoscopy revealed multiple gastric hyperplastic polyps and Hp infection was confirmed by CLO test and histological examination. Reduction in number and size of polyps noted after Hp eradication, and complete disappearance of polyps including a large polyp 18mm in size was found 9 months later. We therefore suggest that in cases of gastric hyperplastic polyps with Hp infection, eradication therapy should be attempted before endoscopic management.