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右頰部結節性筋膜炎-病例報告及文獻回顧

Right Cheek Nodular Fasciitis-A Case Report and Review of Literature

摘要


結節性筋膜炎是一種反應性的良性纖維母細胞腫瘤樣增生,腫瘤多發生於四肢及軀幹,較少見於頭頸部及口腔。臨床上及組織學上與惡性腫瘤相似,生長速度較快,顯微鏡下呈現梭狀細胞浸潤性生長的病理變化,因此又稱爲偽肉瘤性纖維瘤病(pseudosarcomatous fibromatosis)。容易被誤診爲惡性腫瘤,被施予較侵襲性的治療,所以需要正確的診斷與對疾病的瞭解,才可避免因爲過度的治療。結節性筋膜炎的治療方式以手術切除爲主,復發率低。復發時應再次確認病理報告,以避免將肉瘤誤診爲良性腫瘤,而延誤治療。本篇報告爲一例頰部結節性筋膜炎,經切片檢查後施予手術切除,術後復原良好。本文對這個病灶的臨床表徵,發生原因,影像學及病理發現進行討論,和比較台灣與國外對此疾病的特性是否有差異。

並列摘要


Nodular fasciitis (NF) is a benign, reactive lesion, composing of proliferative fibroblasts and myofibroblasts. The lesions were commonly found in the upper extremities and trunk, but rarely in maxillofacial region. Due to the rapid growing feature and storiform histpathologic pattern, the lesions were frequently take for mistaken as a malignant tumor. Surgical resection of the lesion is the treatment of choice. Recurrences are rare, but when a lesion recurs, the original pathologic diagnosis should be revised. We report a rare case of NF in a 36-year-old male patient who suffered from a rapidly growing nodule in the right cheek region for one month. He received surgical excision of the tumor and follow-up for one year without recurrence. The clinical, pathologic findings, pathogenesis and the treatment opinions are discussed in details, with review of the literatures from Taiwan.

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