並列摘要
Pemphigus vulgaris is a rare autoimmune disease that causes multiple blisters in the oral cavity and skin, a result of antibodies attacking the desmoglein (Dsg), a type of epithelial cell adhesion molecule between keratinocytes. Diagnosis is established with histopathologic and immunologic examination, where acantholysis and intercellular IgG and C3 deposits are noted after immunostaining. We present such a case with a 60-year-old woman complaining of multiple painful oral ulcers that have caused oral bleeding on many occasions. In our article, we discuss the differential diagnosis involved, as well as various treatment protocols available that are recommended today.