- 期刊
人工真皮應用在口腔黏膜下纖維化的治療
Artificial Dermis in the Treatment of Oral Submucous Fibrosis
摘要
目的：本研究的目的，是研究以人工真皮作為取代自體分層皮膚移植，治療口腔粘膜下纖維化病患的結果。材料與方法：28位口腔粘膜下纖維化病患均以人工真皮修復，根據上下門牙齒間距離分為2組。第I組（14名患者）的上下門牙齒間距離為10至19 mm。第II組（14名患者）的上下門牙齒間距離為20至29 mm。紀錄手術前、手術中和手術後上下門牙齒間距離，並分析其變化。結果：所有患者均為男性，而且都有咀嚼檳榔的習慣。第II組病人平均術前上下門牙齒間距離為22.7 mm，大於第I組平均術前上下門牙齒間距離為14.5 mm，是有統計上顯著意義。第II組病人平均術中上下門牙齒間距離為38.6 mm，大於第I組平均術中上下門牙齒間距離為22.9 mm，是有統計上顯著意義。在病人最後追蹤的上下門牙齒間距離，第I組是22.9 mm和第II組是28.1 mm，兩組之間無顯著差異。最後追蹤的上下門牙齒間距離的淨增量，第I組是8.4 mm和第II組是5.4 mm，兩組之間無顯著差異。結論：口腔粘膜下纖維化病患的治療，人工真皮可以當作自體分層皮膚移植的替代物。
並列摘要
Purpose: The aim of this study was to investigate the results of artificial dermis as a substitute for split-thickness skin graft in the treatment of oral submucous fibrosis (OSF). Materials and methods: 28 OSF patients treated with artificial dermis. These patients were divided into 2 groups by interincisal distance (ID). The ID of Group I (14 patients) was from 10 to 19 mm. The ID of Group II (14 patients) was from 20 to 29 mm. The serial IDs (preoperation, intraoperation, and postoperation) were investigated and analyzed. Results: All the patients were males and habitually chewed betel quid. The mean preoperative ID of group II (22.7 mm) was significant greater than group I (14.5 mm). The mean intraoperative ID of group II (38.6 mm) was significant greater than group I (33.9 mm). The final follow-up ID was no significant difference between group I (22.9 mm) and group II (28.1 mm).The net incremental IDs were no difference between group I (8.4 mm) and group II (5.4 mm) at the final follow-up. Conclusions: Artificial dermis can be an alternative to split thickness skin grafts in patients with OSF.