- 期刊
Malignant Follicular Infundibulum Tumor-A Case Report
惡性毛囊漏斗部腫瘤－案例報告
摘要
背景： 從皮膚附屬器官衍生出的毛囊漏斗部腫瘤很罕見，Mehregan及Butker於1961年第一次提出後，也僅有少數幾例報告，且多爲良性，惡性變化則少見。其不特殊的臨床特徵，常誤判爲基底細胞癌。正確的診斷須藉由病理檢查。 目的及目標： 在此我們提出一例此腫瘤併惡性變化的案例報告，及回顧有關其臨床表徵、特殊的病理特徵、與手術治療的文獻。 材料及方法： 一位九十八歲的婦人，主述三個月前右臉了出現一顆中央潰瘍的腫瘤，並於兩個月間從直徑一公分增大至三公分。病人接受大範圍切除並從右鎖骨皮膚取皮植皮。 結果： 病理報告證實爲毛囊漏斗部腫瘤併惡性變化。於術後十二個月的追蹤，病人滿意手術部位的外觀，且無相關併發症及復發跡象。 結論： 毛囊漏斗部腫瘤併惡性變化是非常罕見的。無論良性或惡性，診斷方式不能僅靠臨床表現，必須藉由病理檢查。大範圍切除病灶並從他處取全層皮膚移植是個可行的手術方式，且可達到令人滿意的結果。
關鍵字
無資料並列摘要
Background: Follicular infundibulum tumor that derived from the skin adnexa is very unusual. Most reported cases were benign tumor, rarely with malignant change in the literature. It is easily misdiagnosed because of the non-specific clinic features. Aim and objectives: Herein we present a case with this uncommon skin tumor with malignant change, and review previous literature including clinical presentation, specific histopathologic characteristics, and surgical treatment. Materials and Methods: A 98-year-old woman complained of a solitary ulcerative skin tumor over the right cheek three months ago. The tumor grew rapidly from one to three centimeters in diameter in recent two months. Radical ablative surgery was performed and the defect was reconstructed with full thickness skin graft from the right clavicle skin. Results: The pathology report was follicular infundibulum tumor with malignant transformation. After twelve months follow-up, the patient was satisfied with the functional and cosmetic outcomes. There was no sign of recurrence. Conclusion: Malignant follicular infundibulum tumor is a very rare neoplasm. It is difficult to diagnose correctly according to the clinical presentation. Histopathologic examination is necessary not only for differential diagnosis with other skin tumors but also for benign or malignant proves. Wide excision of the malignant lesion and immediate reconstruction is a considerable treatment to achieve satisfactory outcomes.