摘要
Background: A cutaneous horn, also called as "cornu cutaneum", is a clinical medical condition describing a protruding cone- or cylinder-shaped skin lesion that resembles an animal's horn. It can be derived from a variety of benign or malignant epidermal diseases, although it contains superficial keratotic material. Therefore, we aimed to determine the common site and definitive pathology of cutaneous horns. Aim and Objective: we aimed to determine the common site and definitive pathology of cutaneous horns. Material and Method: In this retrospective study, we searched our hospital's pathology database using the term "cutaneous horn" between December 2004 and July 2022. All patient data, including demographics, lesion site and size, final diagnosis, and surgical treatment, were collected. Results: This study included 25 patients. The male-to-female ratio was 11:14, and the average age was 70.52 years (27- 95). The most common location of the lesions was the face (84%), followed by the trunk (8%) and limbs (8%). Four cases were malignant (16%), including two basal cell carcinomas, one squamous cell carcinoma, and one keratoacanthoma. Six cases were of actinic keratosis cases (24%), considered premalignant lesions. The other cases included 8 cases of hyperkeratosis (32%), 5 verrucous lesions (20%), and 2 fungal infections (8%). The average volume was 1.8 × 1.2 × 0.8 cm^3. Conclusion: A cutaneous horn occurs mostly on the face, which may be related to sun exposure. The malignancy or pre-malignancy potential of the cutaneous horn was high (40%). We suggest total excision of the lesions, and wide excision is necessary if malignancy is confirmed.
並列摘要
背景：皮角，為一種突出於皮膚的病灶，顧名思義，其外觀長得像是動物的角一般。外表雖會覆蓋一層角質化細胞，但其內造成的病因卻不盡相同。本篇文章，即是探討皮角的形成原因，並瞭解其為惡性腫瘤的機會。目標：收集並分析皮角案例，藉此瞭解其組成原因及惡性機率。方法：從我們醫院的病理資料庫搜尋“Cutaneous horn”，搜尋期間為2004年12月至2022年07月，並統計病患性別、年齡、病灶部位、病灶大小、病理組成及治療方式。結果：總共蒐集到25位病人，分別在不同部位有不同大小的皮角。男性有11位，女性有14位；平均年齡為70.52歲（範圍從27至95歲，中位數為75歲）；皮角最常發生的部位為面部（84%），其次為軀幹（8%）及四肢（8%）。25個病例中，有4個是惡性腫瘤（16%）（包含2個基底細胞癌、1個鱗狀上皮細胞癌及1個角化棘皮瘤）、6個癌前病變腫瘤（24%）（皆為日光角化症）。其餘還有8個過度角化（32%）、5個疣狀病灶（20%）及2個皮膚黴菌感染（8%）。平均大小為1.8 × 1.2 × 0.8立方公分，體積最大達5.0 ×4.0 × 4.0立方公分。結論：皮角好發於易曝露在日光照射的身體部位，如面部。其有許多不同的內在病理成因，但有高機率的惡性腫瘤或癌前病變可能。對於皮角的處置，我們建議應給予切除，甚至，一旦確認為惡性腫瘤，需做廣泛性切除及必要的重建手術。