隱球菌腦膜炎之一例

A Case of Cryptococcal Meningitis

黃丙丁(Pin-Ting Huang)

《Acta Paediatrica Sinica》 4卷4期 (1963/12) Pp. 270-273

摘要

由於對隱球菌性腦膜炎的驚覺提高，腦脊髓液檢查的進步，在臺灣已有二例的小兒隱球菌性腦膜炎的報告。本小兒症例為第三報告例，係7歲男孩，因腦膜症狀住院，住院當日由腦脊髓液發見有腦膜炎所見並有多數隱球菌後又由培養及動物實驗證明該隱球菌爲Cryptocccus neoformans，經治以Trychomycin 10日後未見效死亡。

並列摘要

A 7-year-old boy, native of Taiwan, was admitted on October 26, 1963 with the complaints of abdominal pain, vomiting and convulsion for two weeks. On admission, he was found to have abdominal pain, convulsion, papilledema, emaciation, and abnormal findings in the cerebrospinal fluid including increased pressure, positive Pandy test, and low sugar content but no pleocytosis. Cryptococcus neoformans was found in the cerebrospinal fluid by direct smear and comfirmed by culture on Sabouraud's medium. Skull x-ray films showed incresed digital markings and separation of sutures. No active lung lesion was demonstrable in the chest x-ray film. Trychomycin, 80,000 units per day, divided into 4 doses, and potassium iodide, 0.3gm. per day, were administered but the patient fell in a comatous state and died on the 10th hospital day.
This is the third and the youngest case of cryptococcal meningitis in children reported in Taiwan.