Prolonged Obstructive Jaundice in Infancy Ⅲ. Congenital Biliary Atresia: Report of 10 Proved Cases

嬰兒之延長性阻塞性黃疸Ⅲ．先天性膽道閉塞症10個證實病例之報告

郭哲舟(Cho-Chou Kuo) ； 盧俊哲(Tsung-Cho Lu) ； 洪文宗(Wen-Tsung Hung)

《Acta Paediatrica Sinica》 7卷2期 (1966/06) Pp. 90-97

摘要

在1954年2月至1964年2月的10年間，臺大醫院小兒科有10例經關刀或解剖證實之先天性膽道閉塞症，包括9例肝外膽道閉塞及1例肝內膽道閉塞而具有正常肝外膽道。此10例於著者等之40例嬰見延長性阻塞性黃疸之一般研究報告中曾略有提述。本文簡述這10例的臨床症狀，實驗檢驗結果，及病理變化。10例中男性有6例女性有4例，其追踪期間為2個半至14個月，皆在生後14個月前死亡。10例皆為外科手術上無法矯正，而沒有1例曾試過矯正手術。并沒有發現家族性病例。
本文並論及本症與他型嬰兒延長性阻塞性黃疸的鑑別診斷。

並列摘要

During the ten year period, from February 1954 to February 1964, there were 10 cases of congenital biliary atresia, including 9 of extrahepatic and one of intrahepatic type, admitted to the Pediatric Ward of the National Taiwan University Hospital. They constitute a quarter of the 40 cases of prolonged obstructive jaundice observed during the same period. The sex distribution is 6 male and 4 females. The diagnoses were all proved, in 6 cases by autopsy and in 4 by surgical operation. They were followed up for 2 to 14 months. All 10 cases died before 14 months of age. All of them were found to be surgically inoperable and in none of them surgical correction was attempted. The clinical records, operation findings and autopsy notes were analyzed and the results are presented.
The differential diagnosis between congenital biliary atresia and other types of prolonged obstructive jaundice in infancy is also briefly discussed.