1967年元月至1971年十二月五年間在臺大醫院小兒科住院患者中有36名經細菌培養證實為格蘭氏陰性細菌的感染。本文乃將此36名患者之臨床經過作分析比較。36名中新生兒佔18名,而一個月至一歲者有10名,一歲至兩歲者有3名,兩歲以上者只有5名。男女比例為1.40.細菌感染前病人之身體狀況與疾病致死率有密切的關係,患有嚴重疾病如白血病者致死率最高(4/5或80%)新生兒患者常見之症狀為體溫異常,拒食及黃疸,新生兒以外的18名患者均有發燒的現象。在本篇報告中Klebsiella aerobacter與Pseudomonas aeruginsa為兩種最常見的細菌。Garamycin對格蘭氏陰性細菌感染之治療有很好的效果。
A retrospective study was made by reviewing clinical records of 36 children with gram-negative bacterial infection during the 5 year period of 1967 through 1971. Among them, 18 cases were newborns, 13 cases between one month and two years of age and five children older than two years of age. The male/female ratio is 1.40. The fatality rate was highest in those patients with underlying fatal diseases. The common clinical features in newborns were abnormal body temperature, poor feeding and jaundice. Fever was constantly present in 18 cases other than newborn infants. Klebsiella aerobacter and Pseudomonas aeruginosa were the two most commonly encountered bacteria in this series. Garamycin gave prompt improvement and favorable outcome.