Humoral and Cellular Immunity in Asthmatic Children: Ⅱ. Immunoglobulin E in Asthmatic Children

氣喘病兒之體液性及細胞性免疫力之研究：Ⅱ.氣喘病兒之免疫球蛋白E之研究

謝貴雄(Kue-Hsiung Hsieh)

《Acta Paediatrica Sinica》 17卷2期 (1976/06) Pp. 70-78

摘要

Serum immunoglobulin E (IgE) concentrations in 60 children with bronchial asthma, 20 healthy children and 20 healthy adults were determined by both radioimmunoassay and single radial immunodiffusion methods, and the relation between serum IgE and clinical spectrum of asthma was analysed. The mean serum IgE in asthmatic children was higher than that in healthy controls (p＜0.03). The Patients with allergic type of asthma, positive skin tests and recent attack had higher serum IgE than the Patients without those characteristics had. The patients receiving longer duration of hyposensitization tended to have lower, though not statistically significant, serum IgE.

並列摘要

Serum immunoglobulin E (IgE) concentrations in 60 children with bronchial asthma, 20 healthy children and 20 healthy adults were determined by both radioimmunoassay and single radial immunodiffusion methods, and the relation between serum IgE and clinical spectrum of asthma was analysed. The mean serum IgE in asthmatic children was higher than that in healthy controls (p＜0.03). The Patients with allergic type of asthma, positive skin tests and recent attack had higher serum IgE than the Patients without those characteristics had. The patients receiving longer duration of hyposensitization tended to have lower, though not statistically significant, serum IgE.