Simple Febrile Convulsions in Children a Retrospective Clinical and Follow-Up Study

小兒單純發熱性痙攣之回顧性追踪研究

張美惠(Mei-Hwei Chang) ； 沈友仁(Yu-Zen Shen)

《Acta Paediatrica Sinica》 19卷1期 (1978/03) Pp. 16-25

摘要

Febrile convulsion is a commom problem in children. From 1971 to 1976, there were 44 cases of simple febrile convulsion followed up at the Pediatric Neurologic Special Clinic (PNSC) of National Taiwan University Hospital. They included 30 males and 14 females. All patients had their age of onset before 3 years of age. Most of their febrile convulsions were accompanied with upper respiratory tract infection, diarrhea, or pneumonia. The positive family history was noted in 35% of these patients. After a mean follow-up duration of 38.3±28.8 months from onset for 24 cases, we found that the recurrence rate of seizure was 72.7% and subsequent afebrile seizures occurred in 13.2% of our patients. There were more recurrences in patients with their age of onset between the 6th and 12th month and in female patients (P＜0.05). The patients with their age of onset below the 6th month and with more than 5 times of seizures had higher rate of subsequent afebile seizures. We used the scores obtained in the follow-up psychometric evaluation for comparison. Their means of the quotients for the receptive communication skills were 88.74±18.51, for the expressive communication skills 83.65±29.59, for the fine motor function 84.00±23.05, and for the gross motor function 88.76±20.77. We also found that their follow-up developmental scores were strikingly influenced by the number of recurrent afebile seizure, but less by the developmental milestones when the first seizure occurred.

並列摘要

Febrile convulsion is a commom problem in children. From 1971 to 1976, there were 44 cases of simple febrile convulsion followed up at the Pediatric Neurologic Special Clinic (PNSC) of National Taiwan University Hospital. They included 30 males and 14 females. All patients had their age of onset before 3 years of age. Most of their febrile convulsions were accompanied with upper respiratory tract infection, diarrhea, or pneumonia. The positive family history was noted in 35% of these patients. After a mean follow-up duration of 38.3±28.8 months from onset for 24 cases, we found that the recurrence rate of seizure was 72.7% and subsequent afebrile seizures occurred in 13.2% of our patients. There were more recurrences in patients with their age of onset between the 6th and 12th month and in female patients (P＜0.05). The patients with their age of onset below the 6th month and with more than 5 times of seizures had higher rate of subsequent afebile seizures. We used the scores obtained in the follow-up psychometric evaluation for comparison. Their means of the quotients for the receptive communication skills were 88.74±18.51, for the expressive communication skills 83.65±29.59, for the fine motor function 84.00±23.05, and for the gross motor function 88.76±20.77. We also found that their follow-up developmental scores were strikingly influenced by the number of recurrent afebile seizure, but less by the developmental milestones when the first seizure occurred.

並列關鍵字

febrile convulsion ； simple febrile convulsion ； epilepsy precipitated by fever ； recurrent afebrile seizure