新生兒細菌性腦膜炎

自民國70年7月至77年7月，曾在本院病嬰室或新生兒加護病房住院的病嬰中，我們共發現了27位患有新生兒細菌性腦膜炎的病例。其中足月兒有20例，早產兒有7例，出生體重小於2500公克的有5例。在懷孕或生產過程中，有早期破水超過24小時併發症者有3例，根據病嬰發病的年齡，分成兩種型式，其中出生後7天內發病的，為早發型，有12例；而晚發型的，則為出生7天以後才發病的，有15例。臨床症狀以發燒、餵食欠佳、呼吸窘迫、活動力減退、腹脹和黃疸為主，另外抽搐、嘔吐和前囪門膨出也是常見的。在這27例中，由E.coli引起腦膜炎佔最多共9例。預後方面，6例死亡，佔22.2%; 6例有明顯的後遺症，佔22.2%。綜合以上，我們以回顧的方式，就過去七年的時間，所經歷的27例新生兒細菌性腦膜炎，分別記懷孕週數、發病年齡、臨床症狀、致病菌種和預後等加以分析，以供參考。

關鍵字

無資料

並列摘要

A retrospective study of the clinical features and management of 27 newborns with meningitis is presented. All were treated in the China Medical College Hospital between July 1981 and July 1988. Seven were premature and twenty were full term. There were 11 males and 16 females. Five infants had low birth weight (＜ 2500g) and 12 cases were diagnosed in the first week of life (early onset). E.coli was the predominant pathogen. The most common presenting manifestations were nonspecific in nature-fever, poor feeding, respiratory distress and poor activity, etc... Six patients died during the period of acute illness and the case fatality rate was 22.2%. Of the 21 patients who survived, six had sequelae (four hydrocephalus, one subdural effusion, one microcephaly), giving an over-all rate of 19 percent in the survivors. The presence of gram-negative bacterial infection and high protein content in CSF correlated significantly with the higher mortality rate.

並列關鍵字

bacterial meningitis in neonate ； Escherichia coli ； group B streptococcus

國際替代計量

新生兒細菌性腦膜炎

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