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Rhabdomyolysis Syndrome in Children: Report of Three Cases

兒童橫紋肌分解症候群:三病例報告

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摘要


我們在小兒加病房觀察到三個病人在病程中合併橫紋肌分解症候群,它的共同特點有橫紋肌酵素CPK、LDH、GOT升高:血清尿酸、血鉀、無機磷升高;血鈣下降併發之抽筋、尿液有潛血反應但無紅血球-即因肌球蛋白尿;他們都有急性腎衰竭。其中一人因肺衰竭死亡,其病理解剖顯示胸腔內有多種異常。另外兩例完全恢復正常。三例都合併感染。 早期診斷橫紋肌分解症候群的重要性在於它有極高的治癒性,對於有發生抽筋及電解質、生化檢查異常的急性病童,要高度考慮此症。治療重點在引導利尿,以防止肌球蛋白尿造成腎衰竭。

關鍵字

無資料

並列摘要


Three cases with distinct clinical manifestations associated with rhabdomyolysis syndrome were encountered in this hospital’s pediatric intensive care unit. Elevation of serum creatine phosphokinase, uric acid, potassium, inorganic phosphate and hypocalcemia with seizure were noted. The three patients all had signs of acute renal failure. One died of respiratory failure, and autopsy revealed multiple intrathoracic anomalies. The remaining two recovered completely from rhabdomyolysis. It is of importance to early recognize any acutely ill patient as having rhabdomyolysis syndrome when there is elevation of muscle enzymes, hypocalcemic seizure, positive orthotolidine reaction of urine strip while negative finding of red blood cell. The syndrome may damage the kidneys. Appropriate management to induce diuresis usually can salvage this potentially life-threatening condition.

並列關鍵字

Rhabdomyolysis

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