Serious Suppurative Group A Beta-hemolytic Streptococcal Infection in Previously Well Children: Report of Six Cases

健康小孩的嚴重A族、β-溶血性鏈球菌感染：六病例報告

黃富源(Fu-Yuan Huang) ； 許忠信(Chung-Sin Hsu) ； 張功樑(Kuo-Liang Chang)

《Acta Paediatrica Sinica》 35卷2期 (1994/04) Pp. 163-169

https://doi.org/10.7097/APS.199404.0163

摘要

最近嚴重的A族、β-溶血性鏈球菌感染不論在大人或小孩都有明顯增加的趨勢，從1981年12月6日至1991年1月19日，本院六例原先健康的小孩發生了嚴重的A族、β-溶血性鏈球菌感染，有五例是發生在最近兩年內。其中一例酷似文獻報告的“toxic shock-like syndrome”，一例是敗血症，兩例是關節炎，另外兩例是新生兒，分別是發生蜂窩組織炎合併敗血症，及發生膿胸合併敗血症。在治療上，及早診斷並立即給予青徵素（20萬至40萬單位／公斤／天）是極爲重要的。若同時有膿胸，需要加上胸管引流，若侵犯到髖關節則需加上外科手術清除及引流。兩位關節炎病人後來都留下輕微跛行的後遺症，其餘四例則都完全康複。

並列摘要

Recently, among adults and children, an increase in the incidence of invasive disease caused by group A betahemolytic streptococcus (GABHS) has been noted. From December 6, 1981 to January 19, 1991, we experienced six cases of serious infection caused by GABHS in previously well children. Among them, five cases were found in recent two years. The clinical manifestations were varied. One child had sepsis, one had streptococcal toxic shock-like syndrome, two had pyogenic arthritis, and the other two newborn infants had empyema and cellulitis associated with sepsis. Early diagnosis and treatment with appropriate antibiotic are necessary for a good outcome. In addition, empyema and pyoarthritis of the hip often need surgical drainage.

並列關鍵字

group A beta-hemolytic streptococcus ； empyema, arthritis ； streptococcal toxic shock-like syndrome