Serum Osteocalcin Levels of Normal Children in Taiwan

台灣兒童骨質素的參考值

羅少甫(Shao-Fu Lo) ； 黃璟隆(Jing-Long Huang) ； 陳力振(Li-Chen Chen) ； 葉國偉(Kuo-Wei Yeh) ； 顏大欽(Dah-Chin Yang) ； 謝貴雄(Kue-Hsiung Hsieh)

《Acta Paediatrica Sinica》 38卷6期 (1997/12) Pp. 443-447

https://doi.org/10.7097/APS.199712.0443

摘要

骨質素主要由造骨細胞分泌，擴散進血液後可以用多種實驗方法檢來。本研究以固相螢光免疫吸附法定量骨質素，這是現今實驗室所常採用檢測微量物質濃度的一種完備且正確的好方法。總共312位小朋友中，178位男孩及136位女孩組成我們的母群體。年齡分布1至15歲間；我們得到如下三項結論(1)骨質素值分布於20到50ng/ml間(2)兩性隨年齡愈接近青春期骨質素值愈高(3)女生在青春期中期這前的骨質素值皆比男生高(2到11歲間且統計學上有意義)。

關鍵字

骨質素 ； 年齡 ； 性別 ； 參考值 ； 青春期

並列摘要

Osteocalcin is mainly secreted by osteoblasts, and then diffuses into blood which can be detected by several experimental methods. This study determined the osteocalcin level by solid phase fluorescent immunosorbent assay (Pharmacia CAP; Sweden), a well-established and accurate laboratory method for determining the minor concentration of substances in blood. A total of 332 healthy children were enrolled in the study, including 176 boys and 156 girls ranging in age from one to fifteen years. It was concluded that (1) quantitative osteocalcin (OCs) value varies between 30.2 to 41.0 ng/ml; (2) there is an incremental tendency in both sexes until puberty; (3) girls generally have a higher osteocalcin level than boys before mid-puberty (2-42 years old). The differences are statistically significant.

並列關鍵字

normal reference range ； puberty ； osteocalcin