Absolute Ethanol Embolotherapy for Hemangioma with Kasabach-Merritt Syndrome

純乙醇栓塞治療合併Kasabach-Merritt症候群之血管瘤

楊曜旭(Yao-Hsu Yang) ； 李秉穎(Ping-Ing Lee) ； 林凱信(Kai-Hsin Lin) ； 曾旭明(Yuk-Ming Tsang)

《Acta Paediatrica Sinica》 39卷1期 (1998/02) Pp. 51-54

https://doi.org/10.7097/APS.199802.0051

摘要

此篇報告敘述一個兩天大女嬰於右大腿出現不規則瘀青而後突顯一血管瘤。三個月大時併發血小板低下、消耗性凝固異常、貧血、心臓衰竭。在Kasabach-Merritt症候群的診斷下，我們施以類固醇、日日春生物堿(Vincristine)、幹擾素、及輸注大量血小板。然而，血小板仍舊低下，血管廇亦逐漸增大。四個月大時，我們以5毫昇純酒精對供應血管瘤的動脈做栓塞治療。三十天後，血小板回復正常，血管瘤也逐漸縮小。本病例說明：針對血管瘤合併Kasabach-Merritt症候群，當內科療法無效時，純酒精栓塞治療不啻爲一有效的治療方法。

關鍵字

血管瘤 ； Kasabach-Merritt症候群 ； 純酒精栓塞治療

並列摘要

This report describes a female baby having a hemangioma over the right thigh that had appeared as an irregular bruise since two days old. Severe thrombocytopenia, consumptive coagulopathy, anemia, and heart failure developed at three months old. With a diagnosis of Kasabach-Merritt syndrome, systemic corticosteroid, vincristine, subcutaneous a-interferon, and massive platelet transfusion were given. However, the platelet count remained low and the skin lesion enlarged gradually. Trans-feeding- arterial embolotherapy with a 5ml pure ethanol (I ml/kg) injection was performed at four months of age. Thirty days later, her platelet count recovered and the hemangioma shrinked in size. This case illustrates that absolute ethanol embolotherapy is an effective treatment for hemangioma with Kasabach-Merritt syndrome and may be life-saving for those with lesions refractory to medical therapy.

並列關鍵字

hemangioma ； Kasabach-Merritt syndrome ； absolute ethanol embolotherapy