Urticaria is a disease pattern of root vacuity and tip repletion. Modern medicine is expert in treatment for tip repletion pattern. Chinese medicine is expert in treated root vacuity pattern or root vacuity and tip repletion pattern. The with diagnosed case male fifty seven years was a chronic urticarial recurrent attack for many years. The chronic urticarial cause of lung-defense vacuity, so wind evil easily invaded skin and induced wind wheals, itchy wind papules, face reddish, sweating and dry mouth. The pathological mechanism of chronic urticarial was liver channel wind-heat. The principle treatment of chronic urticarial governs course wind and dissipate evil, nourish yin and clear heat, as well as drain fire and resolve toxin. The prescriptions were used Wind-Dispersing Powder and Coptis Toxin-Resolving Decoction, adding trichosanthes root, anemarrhena or ophiopogon. After treatment with Warm Clearing Beverage and Wind-Dispersing Powder, the patient's urticarial lesion was not recurrence, but not complete remission. Because of his root vacuity pattern was not received therapy, the future should be have chances of recurrent attack.