- 期刊
Postoperative Pain Relief in Primigravida Caesarean Section Patients-Combination of Intrathecal Morphine and Epinephrine
初次剖腹產病人的術後止痛－經脊髓腔合併注射嗎啡及腎上腺素
摘要
背景：初産婦的子宮收縮疼痛比較輕徽。所以剖腹産時利用脊髓腔注射嗎啡及腎上腺素，可能是一個簡單而有效的術後止痛方法。 方法：報告中收集28位初産婦進行剖腹産手術，並要求做術後止痛者，在脊髓麻醉時注入0.2mg morphine, 0.1mg epinephrine及10mg bupivacaine。另外30位初産婦的控制組病人，則注入normal saline 0.2mL, 0.1mg epinephrine及10mg bupivacaine。我們記錄二組病人術中及術後的並發症及48小時內所需的止痛藥量。 結果：在研究組中，89.3%的病人於手術後的住院期間並不需要止痛藥物，7.1%的病人在術後48小時內，只需要一次Demerol 50mg的肌肉內注射。在控制組中，所有病人在術後48小時內均接受肌肉內注射Demerol 50mg6-7次。二組病人均未發生呼吸抑制。 結論：報告中顯示，初産婦進行脊髓麻醉時，注入0.2mg morphine,0.1mg epinephrine及10mg bupivacaine，能提供一個簡單方便的術後止痛方法。
並列摘要
Background: Uterine contraction is less severe in primigravida patients. Intrathecal coadministration of morphine and epinephrine may provide an easy way of postcaesarean pain control. Methods: Twenty-eight primigravida patients who requested postcaesarean pain control were studied for the effectiveness of coadministration of intrathecal morphine and epinephrine. The solution for spinal anesthesia which contained 0.2mg morphine, 0.1 mg epinephrine and 10mg hyperbaric bupivacaine was injected intrathecally. Another 30 primigravida patients were collected randomly as control. In the control group, normal saline and 0.1 mg epinephrine were used with bupivacaine. Side effects from intrathecal morphine and the need of analgesia were recorded within 48 h. Results: In the study group, 89.3% (25/28) of patients did not need further narcotics for pain relief during their hospitalization after caesarean section. 96.4% (27/28) of patients needed only one dose of 50 mgintramuscular meperidine(Demerol) or no narcotic at all for pain relief within 48 h. No respiratory depression occurred. In the control group, each patient received in the average 6-7 doses of 50 mg Demerol for pain control within 48 h. Conclusions: Our results showed that 0.2 mg morphine and 0.1 mg epinephrine in combination with 10 mg hyperbaric bupivacaine given intrathecally could provide a simple way of pain control in primigravida patients undergoing caesarean section.
延伸閱讀
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