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Anesthesia for Emergency Cesarean Section in a Parturient with Undiagnosed Acute Fatty Liver of Pregnancy-A Case Report

硬脊膜外麻醉於未被診斷出妊娠急性脂肪肝的剖腹產-病例報告

摘要


妊娠急性脂肪肝的臨床診斷,未必在住院時能立即確立。當要求麻醉醫師參與時,經常是處於緊急狀況。我們報告一位入院診斷為子癇前症併胎兒窘迫的孕婦,需緊急剖腹產的病例。在無法立即得到凝血實驗室數據前,採用硬脊膜外麻醉,手術後產婦凝血狀況指數快速變化。本例提出我們週產期間的麻醉照護。手術後26天,經肝臟針穿刺病理檢查,確立診斷為妊娠急性脂肪肝。由於我們的案例,當子癇前症孕婦表現出噁心與黃膽,伴隨高膽紅素、高肝臟酶活性、凝血時間PT和PTT延長、或者血小板減少等現象,臨床醫師必須對妊娠急性脂肪肝有高度的警覺。

並列摘要


Few clinical diagnoses of acute fatty liver of pregnancy (AFLP) are established immediately upon admission, while anesthetic interventions are frequently required on an emergent basis. We report a patient with the admitting diagnosis of severe preeclampsia with fetal distress necessitating an emergency cesarean section. An epiduralblock was instituted before laboratory datawere available. Rapid changes of coagulation profiles occurred after delivery. The peripartum anesthetic care of the pregnant woman is presented. AFLP was confirmed by liver needle biopsy 26 days later. Taking our case as an examplification, cliniciansmust have a high suspicion that AFLP may exist in concurrence with preeclampsia when a parturient presents manifestations of nausea, jaundice, elevated bilirubin, elevated liver enzyme activities, prolonged PT and PTT, or thrombocytopenia.

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