臺灣地區市售小兒驚風散類製劑中鉛、汞含量之調查研究

Investigation on Lead and Mercury Content in Marketed Baby Sedative Chinese Herb Drugs in Taiwan

謝伯舟(Po-Chow Hsieh) ； 謝王昭昭(Jau-Jau Wang) ； 劉宜祝(Yi-Chu Liu) ； 劉芳淑(Fang-Sui Liu) ； 鄭建詒(Chien-Yi Cheng)

《藥物食品檢驗局調查研究年報》 3號 (1985/09) Pp. 109-114

https://doi.org/10.6946/ASRNL.198509.0109

摘要

將市售小兒驚風散類製劑179件及其藥材52種，分別以灰化法及硫酸硝酸法處理後，利用原子吸光光度法(Atomic Absorption Spectrometry；AAS)測定鉛及汞之含量。
結果發現前者之含鉛量在100ppm以上者有3件，其中一件高達3,637ppm；其中由藥廠製售之檢體，其含汞量除含朱砂成分者外，其餘均未檢出或在1ppm下。
中藥材52種中，含鉛量超過30ppm者有黃連、青黛、龍骨、代赭石及朱砂等五種，其餘則在30ppm以下或未檢出，含汞量除朱砂原料為53.2~86.8%外，其餘均在1ppm以下或未檢出。

並列摘要

In order to understand the lead and mercury content in Baby, sedative Chinese herb drugs, 179 preparations and 52 herbs of Chinese drugs were analyzed.
Samples were prepared by Ash determination in lead and sulfuric acid-nitirc acid digestion in mercury, then determined by AAS.
Three of 179 preparations were found containing more than 100 ppm of lead, and the highest one was 3,637 ppm. Among 179 samples, there were 48 come from some pharmaceutical factories, but they were all in negligible level of mercury.
Some mineral drugs of herbs, such as Longgu and Cinnabaris, which contained higher level of lead than others. Inspite of Cinnabaris, almost herbs contained less than 1 ppm of mercury.

並列關鍵字

Lead ； Mercury ； Herb ； Baby sedative Chinese herb drugs ； AAS ； Ash determination ； Sulfuric acid-nitric acid digestion ； Mineral drugs ； Longgu ； Cinnabaris