Population fluctuation and control of serpentine leafminer was studied in the experiment. Seasonal occurrence of the leafminer investigated in northern Taiwan from 1994 to 1995 indicated that there were two population peaks of the insect in a year. The first peak appeared steadly in May-June, while the second peak occasionally appeared in October-November. Plastic house cultivation of lettuce was generally considered as the main cause of inducing the outbreak of the leafminer. The chemical screening test in pipehouse and field indicated that 2% Abmectin EC 2000x and 75% Trigard WP 5000x were effective for the control of serpentine leafminer. The yellow sticky paper was effective for mass trapping of adults of serpentine leafminer.