鼻咽癌患者之咽管功能

1984年6月至9月，4個月中，共診治33位鼻咽癌初診病例。在治療前先取得每位病人之純音聽力和鼓室圖，隨彼為嚴重的症候耳裝置鼓室通氣管（grommet），而僅對輕微者和無症候耳施行十字形鼓膜切開術。另取13位志願者之21個正常耳為對照組，以modified inflation-deflation studies，分別求出各耳之opening pressure (OP), closing pressure (CP)，和residual pressure (RP)；在 ANOVA和Wilcoxon rank-sum test下，我們務現有症狀耳與各症狀耳之OP與CP 跟正常耳比較，並無明顯差別；但症狀耳之RP與無症狀耳及正常對照組比較，則顯現極有意義之增高。觀念上，我們不十分理解鼻咽癌以何種方式引起耳咽管功能異常；由本論文之研究數據顯示機能性阻塞實乃造成鼻咽癌病人耳症候之主要因素。另外耳咽管因鼻咽癌之侵租，所涉及的聽力學、病理生理學及解剖病理學之問題亦是本文討論的重點。

關鍵字

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並列摘要

In a 4 month period, from June to Sep-tember, 1984 , we collected 33 fresh cases of nasopharyngeal carcinoma. After pathologic confirmation, we obtained pure tone audiograms and tympanograms before any treatment was given. In the ears with severe symptoms, grom-mets were inserted , while in the mild or sympto-mless ones, a “+” -shaped myringotomy alone was performed. The modified inflation-deflation tubal ventilatory tests were done on most of the ears including 21 normal ears of 13 volunteers which acted as a control group. From this study, the opening pressure (OP), closing pressure (CP) , and residual pressure (RP) of each ear were obtained. We found no statistical significance on OP and CP between the study and control groups. On the contrary, the RP increased significantly in the group of ears with symptoms . We conclude that functional, rather than mechanical obstruction plays a more important role in tubal dysfunction caused by invasion of nasopharyngeal carcinoma of the eustachian tube and its surrounding tissues.

並列關鍵字

Rosenmuller's fossa(R.F.) ； nasopharyngeal carcinoma ； eustachian tube function

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鼻咽癌患者之咽管功能

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