腎臟疾病病人血清離子鈣及免疫反應性副甲狀腺素之研究

Study of Serum Ionized Calcuim and Immunoreactive Parathyroid Hormone in Patinents with Renal Disorders

陳鴻鈞(Horng-Jiun CHEN) ； 賴永勳(Yung-Hsiung LAI) ； 蘇義華(Yih-Hwa SU) ； 蔡瑞熊(Juei-Hsiung TSAI)

《The Kaohsiung Journal of Medical Sciences》 1卷3期 (1985/03) Pp. 188-194

https://doi.org/10.6452/KJMS.198503.0188

摘要

Serum ionized calcium and immunoreactive parathyroid hormone(iPTH) were analyzed in 20 normal adults (group 1) and 81 patients with renal disorders including nephrotic syndrome with normal renal function, 10 patients (group 2A) ; nephrotic syndrome with impaired renal function, 8 patients (group 2B); acute renal failure ,10 patients (group3) ; chronic renal failure, 33 patients (group4); and uremia on maintenance hemodialysis, 20 patients (groups).
The mean serum ionized calcium and the mean serum iPTH were: group l , 4.73±0.04 mg/dl and 88±5 pmo1/l; group 2A, 4.10±0.10 mg/dl and 105±7 pmol/1; group 2B, 4.17 ±0 . 32 mg / dl and 287±109 pmo1 / l ; group3 , 4 . 09±0 . 17 mg / dl and 333±57 pmol / l; group 4 , ' 4 . 28±0.21 mg / dl and 680±129 pmo1/l ; and groups, 4.35±0.12 mg / dl and 1824±395 pmo1 / 1. In all groups of patients, the mean serum ionized calcium was lower and the mean serum iPTH was higher than normal. However, significant negative correlations between serum ionized calcium and iPTH were present only in group 4 (r＝-0.568, p ＜ 0.001).
These results indicate that in patients with various renal disorders, correlations between serum ionized calcium and iPTH become rather complicated due to the influence of many factors.

並列摘要

Serum ionized calcium and immunoreactive parathyroid hormone(iPTH) were analyzed in 20 normal adults (group 1) and 81 patients with renal disorders including nephrotic syndrome with normal renal function, 10 patients (group 2A) ; nephrotic syndrome with impaired renal function, 8 patients (group 2B); acute renal failure ,10 patients (group3) ; chronic renal failure, 33 patients (group4); and uremia on maintenance hemodialysis, 20 patients (groups).
The mean serum ionized calcium and the mean serum iPTH were: group l , 4.73±0.04 mg/dl and 88±5 pmo1/l; group 2A, 4.10±0.10 mg/dl and 105±7 pmol/1; group 2B, 4.17 ±0 . 32 mg / dl and 287±109 pmo1 / l ; group3 , 4 . 09±0 . 17 mg / dl and 333±57 pmol / l; group 4 , ' 4 . 28±0.21 mg / dl and 680±129 pmo1/l ; and groups, 4.35±0.12 mg / dl and 1824±395 pmo1 / 1. In all groups of patients, the mean serum ionized calcium was lower and the mean serum iPTH was higher than normal. However, significant negative correlations between serum ionized calcium and iPTH were present only in group 4 (r＝-0.568, p ＜ 0.001).
These results indicate that in patients with various renal disorders, correlations between serum ionized calcium and iPTH become rather complicated due to the influence of many factors.

並列關鍵字

ionized calcium ； iPTH ； renal disorders