- 期刊
以超音波心圖評估心血管造影劑對左心室功能之急性期影響
Evaluation of the Acute Effect of Contrast Medium on Left Ventricular Function by Echocardiography
摘要
The acute effect of contrast ventriculography on left ventricular function was evaluated in 20 patients (age 19－60 yrs, mean 34±13). Three to five minutes after injection of contrast medium (urografin-76) into the left ventricle, left ventricular end-diastolic pressure (LVEDP) elevated from 12.5±4.6 to 18.1±6.5 mmHg (p＜0.005). At the same time the left ventricular end-diastolic dimension (LVEDD) and left ventricular end-diastolic volume (LVEDV) determined by echocardiogram increased from 44.5±8.1 to 46.9±7.6 mm and from 89.1±55.8 to 100.6±59.9 cm3 respectively. (p＜0.005) The left ventricular function curve, plotted by LVEDP against stroke volume (SV), was shifted to right upper. There was linear correlation between the change of LVEDP and the change of LVEDV after contrast ventriculography. (r = 0.52) The effect of injection of 0.9% normal saline into the left ventricle was studied in 13 patients before contrast ventriculography. Similar to contrast ventriculography, 0.9% normal saline was injected into the left ventricle. The LVEDP, LVEDD, LVEDV and SV did not show significant changes. We concluded that the increase in LVEDV is one of the main mechanisms which elevates the LVEDP after contrast ventriculography. Comparing with the normal saline group, the volume loading effect was greater when contrast medium was injected into the left ventricle. This is likely due to extraction of water from the extracellular tissue by high osmolality of the contrast medium.
關鍵字
無資料並列摘要
The acute effect of contrast ventriculography on left ventricular function was evaluated in 20 patients (age 19－60 yrs, mean 34±13). Three to five minutes after injection of contrast medium (urografin-76) into the left ventricle, left ventricular end-diastolic pressure (LVEDP) elevated from 12.5±4.6 to 18.1±6.5 mmHg (p＜0.005). At the same time the left ventricular end-diastolic dimension (LVEDD) and left ventricular end-diastolic volume (LVEDV) determined by echocardiogram increased from 44.5±8.1 to 46.9±7.6 mm and from 89.1±55.8 to 100.6±59.9 cm3 respectively. (p＜0.005) The left ventricular function curve, plotted by LVEDP against stroke volume (SV), was shifted to right upper. There was linear correlation between the change of LVEDP and the change of LVEDV after contrast ventriculography. (r = 0.52) The effect of injection of 0.9% normal saline into the left ventricle was studied in 13 patients before contrast ventriculography. Similar to contrast ventriculography, 0.9% normal saline was injected into the left ventricle. The LVEDP, LVEDD, LVEDV and SV did not show significant changes. We concluded that the increase in LVEDV is one of the main mechanisms which elevates the LVEDP after contrast ventriculography. Comparing with the normal saline group, the volume loading effect was greater when contrast medium was injected into the left ventricle. This is likely due to extraction of water from the extracellular tissue by high osmolality of the contrast medium.
延伸閱讀
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