A Study of the Structure and Pathogenesis of Ascaris and Clonorchis Stones

膽色素鈣石在本省膽石症中是屬常見的膽石，而且這種膽石患者經常可以從病患中查出在孩童時期有寄生虫感染的病史，尤其是蛔虫。本研究將已證實從手術終取出五個蛔虫膽石及四個中華肝吸虫之膽石以光學顯微鏡及掃描式電子顯微鏡觀察膽石核心之微細構造，以探對寄生虫造成膽石形成之之角色。蛔虫膽石之形成可以因膽汁中膽色訴鈣成份堆積在蛔虫死屍體上或與虫卵混合在一起慢慢鈣化成膽石，因為虫屍體及虫卵均可以在膽石內發現存在，另一方面也可認為蛔虫寄生在膽管時也很容易造成膽管炎，因此感染膽汁及其不潔物更可加速膽石形成的可能性。膽囊內中華肝吸虫感染時常常可發現黏液混合在肝吸虫之成虫體或小膽石，從這些混合物內可以觀察出黏液及虫卵混在一起，因此這些感染之混合物將是形成膽石的原因之一，尤其從有中華肝吸虫感染病患之膽石核心也可以發現有肝吸虫之虫卵存在，有時候在膽石之核心可以發現有虫體之部份構造物存在。從這些研究，可以證明膽色素鈣石形成原因一部份可以因為蛔虫或中華肝吸虫之感染造成，也就是由於寄生虫之虫體物或虫卵均可以直接參與膽石之形成的。

關鍵字

無資料

並列摘要

Calcium bilirubinate stones which may be closely related to parasitic infection have been frequently seen in Taiwan over the past two decades. The structure of parasitic stones, 5 ascaris stones and 4 clonorchis stones, were studies using a light microscope and a scanning electron microscope. The ascaris stone is formed by the deposition of calcium bilirubinate on either the dead worm or mixed with ova. Both origins can be detected by the study of ascaris stones. Ascaridic cholangitis also contributes to stones formation through the promotion of infected bile and increasing of floating debris. Amounts of mucus mixed with liver flukes and stones can also be found in the gallbladder. Clonorchis ova will mix with mucus and cause stone formation to proceed. Therefore, the clonorchis ova can be found in the matrix of gallstones from the clonorchiasis patient with gallstones. In the mean time, the dead liver fluke can also be a nidus of gallstone formation. It become evident that elements of ascaris or clonorchias such as ova or dead worm can participate directly in the development of the stone formation.

並列關鍵字

gallstone ； ascariasis ； clonorchiasis

國際替代計量

A Study of the Structure and Pathogenesis of Ascaris and Clonorchis Stones

全文下載

主題瀏覽