睪丸生發細胞癌

Germinal Neoplasm of Testis

陳森基(Shun-Ji Chen) ； 楊啟瑞(Chi-Rei Yang) ； 陳厚全(Hou-Chuan Chen) ； 張吉隆(Chi-Lung Chang) ； 黃一勝(Thomas I-Sheng Hwang) ； 蔡宗欣(Tzong-Shin Tzai) ； 彭海祁(Hai-Chyi Peng) ； 張兆祥(Chao-Hsing Chang) ； 吳錫金(Hsi-Chin Wu)

《The Kaohsiung Journal of Medical Sciences》 4卷12期 (1988/12) Pp. 682-687

https://doi.org/10.6452/KJMS.198812.0682

摘要

睪丸惡性腫瘤，在臺灣是少見的疾病。臺中榮民總醫院于過去年內共經歷二十例睪丸惡性病變，其中三例為轉移性病灶外，其餘十七例為原發性病灶，所有的病灶最初均以腹股溝睪丸根除術治療，手術前後並抽取血液樣本測腫瘤標記，同時以胸部X光及腹部電腦斷層掃描後腹腔淋巴結，以決定其臨床分期。對已轉移到後腹腔或病理上能看到血管侵犯之病例，依其細胞種類，給予化學治療或放射線照射。在平均追蹤二十六個月的seminoma群中，屬於第一期者四例，第二期一例，第三期一例。NSGCT群中第一期七例，第二期二例，第三期二例。兩群中第一、二期經治療後均存活下來。第三期之三例在治療後一年內均死亡。我們認為早期治療仍是決定此一癌症癒後之決定性關鍵，而化學治療對惡性睪丸腫瘤有極佳之治療效果。

並列摘要

Testicular neoplasm is rare in this country. In the past five years 20 cases had been diagnosed at VGHTC. Three cases were of metastatic lesions, and 17 cases were primary germinal cell tumors. All suspected cases initially received ultrasound examination to differentiate intratesticular or extratesticular lesion. Intratesticular lesions were all treated by inguinal orchiectomy for the pathological proof. Staging procedures were done including chest X-ray, CT of retroperitoneal lymph nodes and tumor markers. The choice of therapy after orchietomy was according to the cell type and clinical stage. Seminoma and non-seminoma are the main subdivisions of testicular germinal neoplasm. Four cases in germinoma were in stage I, one case in stage II and another one in stage III. In non-seminoma, 7 cases were in stage I, 2 cases in stage II and 2 cases in stage III. All cases in stage I & II have remained alive after treatment. Three cases in stage III died within one year after orchiectomy. The prognosis of germinal testicular neoplasm is determined by early diagnosis and treatment.
Chemotherapy with multidrug formulas also has significant effect on the treatment of testicular germinal neoplasm.

並列關鍵字

testicular neoplasm ； seminoma ； non-seminoma germinal cell (NSGCT)