- 期刊
Clinical Experience on Malaria
瘧疾的臨床經驗
摘要
在過去的十年中，我們分析11位因瘧疾而來高雄醫學院住院的病人的特徵。百分之七十三的病人在東南亞感染瘧疾。有二位病人曾在出國前服預防性藥物。而另外兩例在其他醫院接受抗瘧藥物後復發。臨床症狀及理學檢查無特別之處，包括發燒、畏寒、腹痛及肝脾腫大。百分之六十四的病人對抗瘧藥物反應良好。有對克羅奎因（Chloroquine）及派馬奎（Primaquine）發生抗藥性，甚至對奎寧也發生抗藥性。其中一位發生重度寄生蟲血症、急性腎衰竭低血糖現象，並在治療五天後死亡。對於有懷疑的病人，周邊血液抹片檢查是一單又快速的方法。對克羅奎因及派馬奎發生抗藥性的病例相當常見，尤其是在東南亞受到感染的病人。因此對重病病人，必須儘快改用更強的藥物及更積極的治療。
關鍵字
無資料並列摘要
The 11 cases of malaria admitted to Kaohsuing Medical College Hospital in the past 10 years were analyzed to assess the characteristics of patients who acquired malaria parasite infection. Nine of the patients contracted malaria in Southeast Asia. Two men had received antimalarial chemoprophlaxis before they went abroad and another wto men relapsed after antimalarial treatment. The initial symptoms and signs were nonspecific, including fever, chills, abdominal pain and hepatosplenomegaly. Seven patients responded well to the antimalarial regimens. Two persons developed meningeal malaria. Resistance to chloroquine and primaquine and even to quinine was noted in another two cases. Hypoglycemia was diagnosed in one of latter two patients who developed heavy parasitemia (26%), acute renal failure and died 5 days after treatment. Peripheral blood smear examination is a simple and quick method to make a diagnosis in any suspicious case. Resistance to chloroquine and primaquine is not uncommon, especially in those who acquired the infection in Southeast Asia. Changing to more potent agents and aggressive management in complicated cases is necessary.
延伸閱讀
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- 王寰峯（1990）。瘧疾疫情簡介。疫情報導，6(9)，67-75。https://doi.org/10.6524/EB.199009_6(9).0001
- Hsieh, C. F., Shih, P. Y., & Lin, R. T. (2006). 瘧疾後神經症候群－病例報告. The Kaohsiung Journal of Medical Sciences, 22(12), 630-635. https://www.airitilibrary.com/Article/Detail?DocID=02575655-200612-22-12-630-635-a