Type of Dementia in Taiwan ─ A Prospective Study

台灣痴呆症的類型：一個前瞻性研究

劉景寬(Ching-Kuan Liu) ； 林瑞泰(Ruey-Tay Lin) ； 洪純隆(Sheng-Long Howng) ； 翁資盛(Tzy-Sheng Ueng) ； 王富民(Fub-Min Wang) ； 張琦(Chi Chang)

《The Kaohsiung Journal of Medical Sciences》 8卷6期 (1992/06) Pp. 290-298

https://doi.org/10.6452/KJMS.199206.0290

摘要

We prospectively investigated 100 consecutive inpatients with suspected dementia to evaluate the relative frequency of various type of dementia in a general hospital of Taiwan. Dementia was confirmed in 86 case (86%) according to the dementia criteria of the third revised edition of the Diagnostic and Statisical Manual of Mental Disorders and Clinical Dementia Rating Scale (≥1). In contrast to the western developed contries, vascular dementia (VD) (35%) was the leading type of dementia, followed by Alzheimer's disease (AD) (27%), mixed VD and AD (MIX) (14%), and other degenerative diseases (10%). Ten cases (11.6%) of potentially treatable dementia were identified and 8 of 10 had good improvement after appropriate treatment. There were significant age differences among patients with MIX, AD and VD (p＜0.01). Those with MIX were the oldest (72.12±9.4) followed by AD (69.70±8.52) and VD (64.81±9.12). Males were slightly predominant in this series (male: female = 50:36). A comprehensive clinical investigation including laboratory tests, electroencephalography and CT are necessary in the assessment of demented patients in order to make correct etiological diagnoses which lead to appropriate treatment or meanagement of this terrifying syndrome.

並列摘要

We prospectively investigated 100 consecutive inpatients with suspected dementia to evaluate the relative frequency of various type of dementia in a general hospital of Taiwan. Dementia was confirmed in 86 case (86%) according to the dementia criteria of the third revised edition of the Diagnostic and Statisical Manual of Mental Disorders and Clinical Dementia Rating Scale (≥1). In contrast to the western developed contries, vascular dementia (VD) (35%) was the leading type of dementia, followed by Alzheimer's disease (AD) (27%), mixed VD and AD (MIX) (14%), and other degenerative diseases (10%). Ten cases (11.6%) of potentially treatable dementia were identified and 8 of 10 had good improvement after appropriate treatment. There were significant age differences among patients with MIX, AD and VD (p＜0.01). Those with MIX were the oldest (72.12±9.4) followed by AD (69.70±8.52) and VD (64.81±9.12). Males were slightly predominant in this series (male: female = 50:36). A comprehensive clinical investigation including laboratory tests, electroencephalography and CT are necessary in the assessment of demented patients in order to make correct etiological diagnoses which lead to appropriate treatment or meanagement of this terrifying syndrome.

並列關鍵字

dementia ； Alzheimer's disease ； vascular dementia