類澱粉病可能侵犯身體的任一器官。心臟一旦受到波及,其臨床表現常與類澱粉的沉積呈正相關性;從早期毫無症狀到後來呈現心臟衰竭,心律不整、心絞痛、瓣膜疾病,或侷限型心肌病變,臨床症狀有極大的個人差異,經常造成診斷上的困擾。本病例因嚴重的鬱血性心衰竭而住院。超音波心圖呈現右心室及左心室壁肥厚,心收縮不良,及典型的閃亮顆粒性心肌變化,而其心電圖卻呈低電位變化,顯示心臟類澱粉病的可能性相當大,因此以心導管檢查及心肌活體切片病理檢查加以證實。
A 52-year old male patient presented with resistant congestive heart failure. Echocardiographic findings revealed increased right ventricular (RV) wall thickness in conjunction with concentric left ventricular (LV) hypertrophy, LV systolic dysfunction and a granular sparking myocardial appearance. Doppler assessment showed a restrictive LV and RV diastolic filling pattern. These echocardiographic features combined with low voltage of the electrocardiogram is highly suggestive of cardiac amyloidosis. The diagnosis was confirmed by cardiac catheterization and endomyocardial biopsy.