- 期刊
Relationship between Left Atrial Pressure and Atrial Natriuretic Peptide in Children with Cardiac Disease
左心房負荷增加之心臟病病兒其心房利鈉胜鈦與心房壓力之相關性
摘要
To evaluate the relationship between atrial pressure and the concentrations of atrial natriuretic peptide (ANP) in plasma of children with cardiac disase combined with increased left atrial loading. We extracted plasma ANP through a Sep-Pak C18 cartridge and proceeded to radioimmunoassay. Of the nine children, age from 20 days to 10 years, cardiac diseases included transposition of the great arteries (four cases), regurgitation (one case). The concentrations of ANP in plasma in the left atrium were greater than in the inferior vena cava, and the concentrations of ANP in plasma in the inferior vena cava correlated significantly with the mean left atrial pressure (r=0.89，P＜0.01), and the concentrations of ANP in plasma in the left atrium correlated significantly with the mean left atrial pressure (r=0.85，P＜0.01). This study indicated that left atrial pressure may have an important influence on secretion of ANP in various cardiac conditions.
關鍵字
無資料並列摘要
To evaluate the relationship between atrial pressure and the concentrations of atrial natriuretic peptide (ANP) in plasma of children with cardiac disase combined with increased left atrial loading. We extracted plasma ANP through a Sep-Pak C18 cartridge and proceeded to radioimmunoassay. Of the nine children, age from 20 days to 10 years, cardiac diseases included transposition of the great arteries (four cases), regurgitation (one case). The concentrations of ANP in plasma in the left atrium were greater than in the inferior vena cava, and the concentrations of ANP in plasma in the inferior vena cava correlated significantly with the mean left atrial pressure (r=0.89，P＜0.01), and the concentrations of ANP in plasma in the left atrium correlated significantly with the mean left atrial pressure (r=0.85，P＜0.01). This study indicated that left atrial pressure may have an important influence on secretion of ANP in various cardiac conditions.
延伸閱讀
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