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Fine-Needle Aspiration Cytology of Retroperitoneal Extramedullary Hematopoiesis: A Case Report

後腹腔骨髓外造血之針抽細胞學:一病例報告

摘要


一位69歲男性病人有一個意外發現的左腎門腫瘤。臨床上,它被懷疑是惡性的。針抽細胞學及冰凍切片無法獲至結論,但不能排除是惡性的腫瘤,然而,稍後對於病人的臨床病史,骨髓切片結果,細胞學抹片,及病理組織的綜合判斷,而獲至骨髓外造血的診斷。 這個病例回顧顯示用針抽細胞學診斷骨髓外造血是可行的方法,但是也發現,當臨床病史不明時,在針抽細胞抹片或冰凍切片中,有可能將異常的巨核細胞當成是惡性的細胞。當病人有骨髓異常的病史時,在骨髓外腫瘤的鑑別診斷上,我們應將骨髓外造血的可能性考慮進去。

關鍵字

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並列摘要


We report a 69 year-old man with left renal hilar tumor, which was incidentally detected and clinically suspecterd to be malignanat. Interpreatations of fine-needle aspiration(FNA) and frozen section of this tumor were not conclusive, and originally malignancy could not be ruled out. Later, correlation with the patient’s history and bone marrow biopsy with cytological and histological pictures resulted in the diagnosis of a tumor of extramedullary hematopoiesis(EMH). This case shows the FNA cytology may be a useful method for diagnosing EMH. However, we also demonstrate the potential pitfall of misdiagnosing atypical megakaryocytes as malignant cells on FNA smears, or even in frozen sections, when clinical history and clinical data are not available. EMH should be considered in the differential diagnosis of patients with bone marrow disorders and mass lesions in extramedullary sites.

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