In Vitro Flow Visualization on the Right Ventricular Outflow Reconstruction Utilizing Extracardiac Conduits: Set-Up of Duplicator System and Its Clinical Significance

應用超低溫保存的含瓣膜之homograft管道重建右心室出口(RVOT)是先天性心臟病外科治療中的重要手段之一。然而，心外管道遠期失敗的血行力學原因尚不清楚，體外研究也沒有開展。結合臨床RVOT重建手術的模式，製作順應性的硅橡膠實驗段，建立因應的簡易右心循環模擬系統，連接八蹤顯示儀，以特定的驅動程序驅動，即可觀察流場的特點，採集和記錄實驗的數據。儘管心外管道模型與臨床上應用的心外管道在成角、長度、直徑、彎曲度以及管道吻合方式等方面均不同，但結果仍顯示簡易右心循環模擬裝置具有系統穩定、重覆性佳等特點，符合幾何相似和生理相似的原理。右心循環模擬系統是右心心外管道流場可視化研究成功的先決條件。

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並列摘要

The right ventricular outflow tract (RVOT) reconstruction with cryopreserved valved homograft conduits was one of the most important methods in the surgical management of congenital heart defects. However, the hemodynamics for long-term conduit failure remain uncertain, and in vitro studies have not been conducted. Based on the surgical patterns of RVOT reconstruction in clinical practice, the compliant silicon elastomers were cast, and the simplified duplicator system was set up. When the system connected with an eight-channel recorder, and driven by a specified software, flow patterns were able to be visualized, and data to be collected. The simplified right heart system was stasble and duplicated well as to the characteristics according with laws of similitude in geometry and physiology, although the conduit model is not in accordance with the clinical extracardiac conduit in angulation, length, diameter, curvature and anastomsis fashion. The right heart duplicator system was a prerequisite condition for the successful research of flow fields of the right heart conduits.

並列關鍵字

congenital heart defects ； flow visualization ； right heart duplicator system

國際替代計量

In Vitro Flow Visualization on the Right Ventricular Outflow Reconstruction Utilizing Extracardiac Conduits: Set-Up of Duplicator System and Its Clinical Significance

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