An Indigenous Melioidosis: A Case Report

類鼻疽病是由鼻疽單胞桿菌(Burkholderia pseudomallei)所引起之感染症，其臨床之表現相當多樣化且有致命之可能性。此病好發於東南亞熱帶地區的泰國、越南、緬甸等及澳洲北部。國內於1985年內發現第一位境外移入之病例後，即罕見新例之報告，而本土性之病例則更是少見，。本文報告一例從未有出國病史之40歲男性糖尿病患者，因Burkholderia pseudomallei感染引起嚴重肺炎及敗血症致死之病例。住院前十天，病患以單純之發燒與咳嗽來表現，且病情有短期間內極速加劇，導致急性呼吸哀竭，休克、意識模糊，最後轉送本院加護病房接受進一孫治療。血液培養於住院第五天時培養出Burkholderia pseudomallei，並根據葯物感受性試驗之結果給予適當之抗微生物製劑治療(Ceftazidime, 2g q8h)，但病患仍不幸於住院九天後因嚴重敗血性休克而死已。根據此病例可預知類鼻疽已成台灣之本土性疾病，故在臨床上需將此病例入感染症之鑑別診斷，以期早期診斷與治療，降低死亡。至於此病在台灣之盛行狀況及環境之污染情形則有待進一步之流行病學的研究與調查。

關鍵字

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並列摘要

Melioidosis is a rare but potentially fatal infectious disease in Taiwan, although it has been endemic in Southeast Asia, especially northesst Thailand, and northern Australia. In this article, we report a male diabetes with fulminant pneumonia, and septicemia caused by Burkholderia pseudomallei without traveling abroad before this episode. Productive cough and inter mittent chills, high fever for one week , followed by progressively deterioraging dyspnea, shock , disturbed consciouness status were the major presentations. Blood culture grew B. pseduomallei on the fifth admission day. Unfortunately, the patient died on the 9th admission day, despite intensive care and the broad-spectrum antimicrobial regimen used.

並列關鍵字

melioidosis ； burkholderia pseudomallei

被引用紀錄

王崇一（2009）。類鼻疽菌鞭毛基因單株抗體之製備與應用〔碩士論文，國立屏東科技大學〕。華藝線上圖書館。https://www.airitilibrary.com/Article/Detail?DocID=U0042-2202201313572913

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An Indigenous Melioidosis: A Case Report

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